WAY 163909

CAS No. 428868-32-0

WAY 163909( WAY163909 | WAY-163909 )

Catalog No. M14454 CAS No. 428868-32-0

A highly potent, subtype-selective agonist of 5-HT2C receptor with Ki of 10.5 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 873 Get Quote
50MG 1782 Get Quote
100MG 2250 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    WAY 163909
  • Note
    Research use only, not for human use.
  • Brief Description
    A highly potent, subtype-selective agonist of 5-HT2C receptor with Ki of 10.5 nM.
  • Description
    A highly potent, subtype-selective agonist of 5-HT2C receptor with Ki of 10.5 nM, >20-fold selectivity over 5-HT2A and 5-HT2B receptor subtypes (IC50=212 and 485 nM, respectively); stimulates the mobilization of intracellular calcium in CHO cells stably expressing the human 5-HT2C with EC50 of 8 nM; produces a dose-dependent reduction in food intake in rat (ED50=2.93 mg/kg), also exhibits preclinical antipsychotic-like activity in vivo.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    WAY163909 | WAY-163909
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    5-HT Receptor
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    428868-32-0
  • Formula Weight
    214.31
  • Molecular Formula
    C14H18N2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    [H][C@]1(CCC[C@]21[H])N3CCNCC4=C3C2=CC=C4
  • Chemical Name
    (11R,15R)-7,10-diazatetracyclo[8.5.1.0^{5,16}.0^{11,15}]hexadeca-1,3,5(16)-triene

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Dunlop J, et al. J Pharmacol Exp Ther. 2005 May;313(2):862-9. 2. Marquis KL, et al. J Pharmacol Exp Ther. 2007 Jan;320(1):486-96. 3. Rosenzweig-Lipson S, et al. Psychopharmacology (Berl). 2007 Jun;192(2):159-70. 4. Grauer SM, et al. Psychopharmacology (Berl). 2009 May;204(1):37-48.
molnova catalog
related products
  • Cannabigerol

    Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; also binds to the CB2 receptor; it can relieve interocular pressure, which may be of benefit in the treatment of glaucoma.

  • Ro 67-7476

    Ro 67-7476 is a positive allosteric modulator of mGlu1 receptors. No activity at human mGlu1 receptors. Potentiates glutamate-induced calcium release with EC 50 of 60.1 nM.

  • Buspirone

    Buspirone free base is an agonist of serotonin receptor with anxiolytic activity. Buspirone free base has an efficacy comparable to diazepam.