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WAY 163909
CAS No. 428868-32-0
WAY 163909( WAY163909 | WAY-163909 )
Catalog No. M14454 CAS No. 428868-32-0
A highly potent, subtype-selective agonist of 5-HT2C receptor with Ki of 10.5 nM.
A highly potent, subtype-selective agonist of 5-HT2C receptor with Ki of 10.5 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameWAY 163909
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NoteResearch use only, not for human use.
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Brief DescriptionA highly potent, subtype-selective agonist of 5-HT2C receptor with Ki of 10.5 nM.
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DescriptionA highly potent, subtype-selective agonist of 5-HT2C receptor with Ki of 10.5 nM, >20-fold selectivity over 5-HT2A and 5-HT2B receptor subtypes (IC50=212 and 485 nM, respectively); stimulates the mobilization of intracellular calcium in CHO cells stably expressing the human 5-HT2C with EC50 of 8 nM; produces a dose-dependent reduction in food intake in rat (ED50=2.93 mg/kg), also exhibits preclinical antipsychotic-like activity in vivo.
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In Vitro——
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In Vivo——
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SynonymsWAY163909 | WAY-163909
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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Recptor5-HT Receptor
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number428868-32-0
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Formula Weight214.31
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Molecular FormulaC14H18N2
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Purity>98% (HPLC)
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Solubility——
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SMILES[H][C@]1(CCC[C@]21[H])N3CCNCC4=C3C2=CC=C4
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Chemical Name(11R,15R)-7,10-diazatetracyclo[8.5.1.0^{5,16}.0^{11,15}]hexadeca-1,3,5(16)-triene
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Dunlop J, et al. J Pharmacol Exp Ther. 2005 May;313(2):862-9.
2. Marquis KL, et al. J Pharmacol Exp Ther. 2007 Jan;320(1):486-96.
3. Rosenzweig-Lipson S, et al. Psychopharmacology (Berl). 2007 Jun;192(2):159-70.
4. Grauer SM, et al. Psychopharmacology (Berl). 2009 May;204(1):37-48.
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